Advice from FDA & Pfizer on Designing a Sertraline Withdrawal Schedule
The FDA along with drugmaker Pfizer offer minimal instruction to consumers on how to schedule discontinuation of Zoloft.4 To quote from the drug label here, “Adverse reactions may occur upon discontinuation of ZOLOFT. Gradually reduce the dosage rather than stopping ZOLOFT abruptly whenever possible.”
Imagine if airplane pilots were given a 750 page manual on how to get the plane up in the air, but not given any instructions on how to get the plane safely on the ground. It’s important to have guidelines for pilots. Why are physicians not provided with the same level of training on medication discontinuation?
Careful Navigation Is Key in Zoloft Discontinuation
A sertraline withdrawal schedule requires more deft navigation and understanding than the vague instructions referenced above.
Most SSRIs are prescribed by doctors who have received little to no instruction on coming off SSRI medications safely. Yet the burden of patient care falls on their shoulders.
While we are certain that our program is the most successful one available anywhere, we realize not everyone can attend our inpatient treatment center.
At the very least, find a doctor who is familiar with SSRIs and can help you design your sertraline withdrawal schedule with your comfort and safety in mind.
You can find many such physicians through IMMH.org who may be able to assist or give you referrals. Bottom line is don’t try it on your own. Get good help.
Liabilities of Haphazard or Abrupt Zoloft Cessation
Much research and even the drug label itself acknowledges that abrupt cessation is not a good sertraline withdrawal schedule.5-8
Adverse reactions of a poorly designed sertraline withdrawal schedule can include:
- Seizures
- Mania
- Tremors
- Brain zaps
- Rebound of original symptoms, to a worsened degree
- Agitation
- Anxiety
- Dizziness
- Headache
- Confusion
- insomnia
- Rapidly changing, dramatic emotional episodes
- Tinnitus
- Sweating
- Nausea
Discontinuation symptoms can be extremely harsh as the above list demonstrates. Many doctors and patients may misinterpret these reactions as “relapse” when in fact they are reactions to haphazard or poorly designed withdrawal protocols. A well-designed sertraline withdrawal schedule should reduce dosages extremely gradually over an ample period of time.8